General Quisenberry entered the Air Force in 1979 as a distinguished graduate of the University of Northern Colorado ROTC program. After serving seven years as an intelligence applications officer, she separated from active duty in November 1986. In the Air Force Reserve, she has served as an intelligence individual mobilization augmentee to Pacific Air Forces Command, Air Force Intelligence Agency, Military Airlift Command and Air Force Special Operations Command. She has also been an Active Guard Reserve officer at Headquarters Air Reserve Personnel Center and the U.S. Air Force Academy. Prior to her current assignment, she was mobilization assistant to the Director of Intelligence, Headquarters Air Combat Command.
From February 2010 to September 2010, General Quisenberry served as the Deputy Director, Intelligence, Surveillance and Reconnaissance Directorate, Headquarters U.S. Southern Command, Miami, Fla., in support of Operation Unified Response, the U.S. government's response to the Haitian relief efforts following the January 2010 earthquake.